Pathogenicity and Virulence

Pathogenicity is specifically the characteristic or state of having the capacity to cause illness, whereas virulence is the ability of an organism to cause disease, or the level of pathogenicity within a group or species.Virulence factors are substances generated by microorganisms that cause illness. Toxins, surface coatings that prevent phagocytosis, and surface receptors that bind to host cells are a few examples.

In addition, Salmonella protein SopE, which functions as a GEF and activates the GTPase to produce additional GTP, is one example of a bacterial virulence factor that behaves like a eukaryotic protein. Nothing is changed, but the usual cellular internalisation process is overdriven, which makes it simpler for the bacteria to infiltrate a host cell.

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